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Saturday, April 27, 2013
Vertical Perspective of Hong Kong's Immense Skyscrapers
Gunman kills Hamelin politician then himself - The Local
A 74-year-old gunman killed a top official in the northern German town of Hamelin on Friday before shooting himself dead, police said.
Shots were heard shortly after 10am in the city's main administrative building, where 63-year-old Butte was later found dead along with the body of his assailant.
The attacker was not identified. Police refused to comment on media speculation that the shooter was a gun fanatic but did say that the suspect was known to officers in the area. He used a heavy-calibered revolver to shoot Butte.
Butte was married with two adult children and five grandchildren, according to his profile on the district website. By Friday afternoon, his personal website had been taken off line.
Lower Saxony's Interior Minister Boris Pistorius said in a statement that Butte's murder had left him stunned. ?He will be missed by everyone. My thoughts go to his wife and children.?
He served as a police officer, rising through the ranks to become the head of the State Crime Investigations Office of Lower Saxony from 2001 to 2005. He had served as district administrator of Hamelin-Pyrmont, an elected office, since 2005.
The town is best known for the folk tale of the Pied Piper, later popularised by the Brothers Grimm.
Gun violence is rare in Germany, although major massacres in Erfurt in 2002 and Winnenden in 2009 made headlines around the world.
Gun crime, never high in Germany when compared with many other countries, dropped considerably over the past decade ? in 2000, police registered 19,400 crimes in which involved a firearm. By 2011, this figure stood at 11,700.
Of the 2011 statistics, 5,600 were shootings and 132 were incidents in which a gun was involved in a murder, manslaughter or assisted suicide investigation.
AFP/DPA/The Local/jcw
Source: http://www.thelocal.de/society/20130426-49387.html
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Stocks sputter on tepid US economic growth
NEW YORK (AP) ? The stock market sputtered Friday after the U.S. economy didn't grow as much as hoped. Neither did earnings from a handful of big companies.
Economic growth accelerated to a 2.5 percent annual rate in the first three months of the year, the government said. But it was below the 3.1 percent forecast by economists.
The shortfall reinforced the perception that the economy is grinding, rather than charging, ahead. Investors have also been troubled by reports in the last month of weaker hiring, slower manufacturing and a drop in factory orders.
"There are some concerns as we head into the summer," said JJ Kinahan, chief derivatives strategist for TD Ameritrade. "In the last three weeks, we've have seen numbers that weren't exactly what you'd love to see."
Corporate earnings this week have also contained worrisome signs. Many companies missed revenue forecasts from financial analysts, even as they reported higher quarterly profits. For example, Goodyear Tire slipped 3.4 percent to $12.49 Friday after revenue fell short of analysts' estimates, hurt by lower global tire sales.
Of the companies that have reported earnings so far, 70 percent have exceeded Wall Street's expectations, compared with a 10-year average of 62 percent, according to S&P Capital IQ. However, 43 percent have missed analysts' revenue estimates.
The S&P 500 index fell three points to 1,583, or 0.2 percent, paring its gain for the week to 1.8 percent.
The Dow, however, was up 11 points, or 0.1 percent, at 14,717, lifted by Chevron's stock. Profit for the U.S. oil company beat expectations of financial analysts in the first quarter, pushing shares up $1.29, or 1 percent, to $119.80 on Friday.
The Dow index is 1.2 percent higher this week.
The Nasdaq composite was down 20 points at 3,269, a decline of 0.6 percent. The index is still 2 percent higher this week.
The tech-heavy index has lagged both the Dow and the S&P 500 this year, but led the way higher this week, boosted by Microsoft. The software giant, which makes up 5.3 percent of the Nasdaq, is on track to record its biggest weekly gain since January last year, after reporting earnings April 19 that beat Wall Street expectations and revealing an aggressive push into the computer tablet market.
Even Apple, the largest stock in the Nasdaq, had a good week, advancing 5.8 percent to $413.20, despite posting a decline in quarterly profit Tuesday. Apple accounts for 7.6 percent of the index's value and the weekly gain was its biggest since November.
Among big names that investors were focusing on Friday, Amazon.com fell 7 percent to $255.20 after the company warned of a possible loss in the current quarter. And in the first quarter, the online retailer reported lower income fell as it continued to spend heavily on the rights to digital content. Expedia fell 11 percent to $58.15 after the online travel company's reported a quarterly loss.
Homebuilder D.R. Horton surged 8 percent to $26.48 its income nearly tripled thanks to a continuing recovery the housing market. The results were handily beat the forecasts of financial analysts who follow the company.
J.C. Penney jumped 8.5 percent to $16.52 after the billionaire financier George Soros disclosed that he had taken a 7.9 percent stake in the struggling company.
In government bond trading, the yield on the 10-year Treasury note fell to 1.67 percent from 1.71 percent, its lowest rate of the year.
Source: http://news.yahoo.com/stocks-sputter-tepid-us-economic-growth-184133429.html
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Marathon deaths prompt review of security policy
In this photo taken Wednesday, April 24, 2013, a security guard checks the backpack of a fan entering AT&T Park before a baseball game between the San Francisco Giants and the Arizona Diamondbacks in San Francisco. Major League Baseball's previously scheduled security meeting in New York took on added importance in the aftermath of the marathon bombs. Each team sets its own security standards, although clubs might consider cutting the size of the general major league limitation on bags from 16x16x8 inches to something less.(AP Photo/Jeff Chiu)
In this photo taken Wednesday, April 24, 2013, a security guard checks the backpack of a fan entering AT&T Park before a baseball game between the San Francisco Giants and the Arizona Diamondbacks in San Francisco. Major League Baseball's previously scheduled security meeting in New York took on added importance in the aftermath of the marathon bombs. Each team sets its own security standards, although clubs might consider cutting the size of the general major league limitation on bags from 16x16x8 inches to something less.(AP Photo/Jeff Chiu)
In this photo taken Tuesday, April 23, 2013, fans have their backpacks searched by security personnel prior to entering AT&T Park for a baseball game between the Arizona Diamondbacks and the San Francisco Giants in San Francisco. Major League Baseball's previously scheduled security meeting in New York took on added importance in the aftermath of the marathon bombs. Each team sets its own security standards, although clubs might consider cutting the size of the general major league limitation on bags from 16x16x8 inches to something less. (AP Photo/Ben Margot)
In this photo taken Tuesday, April 23, 2013, security personnel check bags as fans enter the American Airlines Arena before the start of Game 2 of the first-round NBA basketball playoff series between the Miami Heat and the Milwaukee Bucks in Miami. NBA spokesman Tim Frank said, "We regularly practice a wide range of state of the art security measures in all of our arenas." (AP Photo/Wilfredo Lee)
In this photo taken April 23, 2013, a New York City police officer watches as fans stop to have their bags checked by security before entering Citi Field for a baseball game between the New York Mets and the Los Angeles Dodgers in New York. Major League Baseball's previously scheduled security meeting in New York took on added importance in the aftermath of the marathon bombs. Each team sets its own security standards, although clubs might consider cutting the size of the general major league limitation on bags from 16x16x8 inches to something less. (AP Photo/Kathy Kmonicek)
Left unattended, no accessory looks as menacing these days as a backpack.
At the airport. On the subway. At a sports event.
And, as a result of the two backpack-encased bombs that exploded near the finish line at the Boston Marathon, sports teams and leagues around the world are rethinking what kind of bags, satchels, purses and, yes, black nylon backpacks should be allowed inside stadiums and arenas.
The packs will even be the focal point of a conference this summer of stadium-security personnel in Orlando .
"After what happened ... I wouldn't be surprised if the number of people eliminating backpacks would increase," said Lou Marciani, director of the National Center for Spectator Sports Safety and Security, founded in 2006 and based at the University of Southern Mississippi in Hattiesburg.
Next Saturday, more than 165,000 people are expected at Churchill Downs for the Kentucky Derby. Backpacks, duffel bags and large purses have been banned from the track since 2002 ? part of the clamp-down that followed the Sept. 11 attacks. Still, Derby officials have told fans their bags will undergo increased security checks for this year's race.
No matter where the world ends up on the bag-check spectrum, some fans may never again regard the pack slung across their body quite the same way.
"I never really thought about backpacks until last week, and now you notice backpacks all over the place," said Ryan Hershberger of Hartwell, Ga., as he headed into a Colorado Rockies game carrying a black backpack. "It makes you think."
Down the street, at the Denver Nuggets game, a handful of fans shared the same sentiment.
"I've been thinking about it all day," Joel Cross said on the concourse at the Pepsi Center in Denver. He and his wife traveled from Harrisburg, Neb., to attend Tuesday night's Nuggets playoff game. "We're from a community where our whole county only has 600 people in it. Nobody is going to bomb us because there's no one there. But we're coming to a populated area."
The NFL beefed up security for thousands of fans attending its annual draft, which runs through Saturday, with metal detectors, pat-downs and about 20 percent more personnel in place than previous years. Backpacks are banned. The league said it would consider what, if any, changes might be made for the 2013 season, which ends with the Super Bowl in New York next February.
Major League Baseball's security officials met Thursday but Commissioner Bud Selig said no changes are expected in the rules on bags fans can bring to ballparks, generally limited to 16x16x8 inches. The meeting was scheduled before the Boston explosions that killed three and injured more than 260/
"I wouldn't say that Boston has changed anything," Selig said. "Each club makes its own decision."
At Yankee Stadium, for example, briefcases, coolers and other hard-sided bags or containers are not permitted. At Kansas City's Kauffman Stadium, wrapped presents are banned along with cameras with lenses of 12 or more inches. The Baltimore Orioles ban bags with wheels at Camden Yards.
Boston and San Francisco were among the teams opting to use metal-detecting wands on fans and their possessions this week.
"We've added people, and people are getting in faster now, so we're going to stick with the plan," Giants president and CEO Larry Baer said.
Though the marathon bombings caught the attention of the world, not every event or championship, especially overseas, is beefing up or changing security measures.
For instance, officials at Manchester United, the FA Cup final and the European Champions League say their policies, which either ban large bags or strongly discourage them, are under constant review but not set to change.
"We did, of course, contact the police in the aftermath of the Boston bombings, as part of our commitment to the security of fans and visitors to the stadium," Manchester United said in a statement.
At Wimbledon, where tennis action starts in June, no changes are planned.
"It was a terrible event, but we have no reason to believe it's something that has a direct impact on Wimbledon," All-England Club chief executive Richard Lewis said, referring to the Boston explosions.
At the Summer Olympics in London, soft-sided bags were required to fit under seats and couldn't hold more than 25 liters (6 gallons).
Sebastian Coe, who led London's organizing committee, says a ban on backpacks at sports events would not be justified.
"We have to make some pretty tough decisions in the way we want to live our lives," he said. "It's very easy to draw all sorts of conclusions (from the Boston bombings). Do we want to live in a world where people can't wear backpacks to sporting events? I'm not sure we do."
Organizers in Brazil aren't making any radical changes to their backpack policy for the upcoming Confederations Cup or next year's World Cup. So far, the extensive list of prohibited items includes "unwieldy" bags ? no more than 10x10x10 inches and too big to fit under a seat.
Officials in Russia, which hosts the 2018 World Cup, said that whenever a sports-related tragedy occurs, they review what happened "to ensure that our own regulations and procedures are sufficiently covering such potential tragedies or risks."
In Sochi, Russia, site of February's Winter Olympics, security for test events was so stringent that the president of the international skiing federation, Gian Franco Kasper, cracked, "The only moment they didn't inspect our athletes was during the race."
International Olympic Committee member Dick Pound of Canada said one strategy might be to push back security boundaries.
"I remember in Vancouver and other places, the tension between the organizers and the events and the security folks was over the size of the perimeter," Pound said. "If you can move the perimeter back 50 or 100 meters, a backpack bomb is going to have less lethal effect."
In the U.S., NBA spokesman Tim Frank wouldn't comment on specific security practices, beyond saying: "We regularly practice a wide range of state of the art security measures in all of our arenas." The Nuggets have long used wands and searched bags. But Cross' wife, Shelly, said she noticed a more extensive security presence at Tuesday's game than the last time they made the trip to Denver.
"We were here not too long ago and we don't remember this," she said.
At least one backpack developer said she was unaware of any pending changes to basic designs. She also thought the bombings were unlikely to create a need for see-thru or clear backpacks.
"I don't think people want to share their belongings with everyone. Everyone wants their privacy," said Annelies Mertens, a member of the Samsonite development team in Belgium. "I don't think this will have an influence on the way backpacks are made. I don't see that happening."
While the Boston Marathon presented its own set of difficult challenges ? securing a 26-mile course dotted with trash cans and spectators on almost every block ? one expert says there's no such thing as perfect security guidelines, regardless of venue.
"A no-backpack policy is fine if it applies to everyone," said Derek Catsam, an associate professor at University of Texas of the Permian Basin in Odessa who has studied the safety issue in stadiums. "But then you start making exceptions for people with kids, and for the elderly and for women with purses and people in expensive seats. Where does it end? You can have a policy or not have a policy. But once you start selectively enforcing it, that's going to be problematic."
After the bombings, the NHL's Boston Bruins added metal-detecting wands to their security regimen and checked cars parking in a garage underneath the arena. Security measures vary by arena in the NHL. The New York Islanders, for example, don't allow backpacks; the Detroit Red Wings ban oversized bags and search all bags that are allowed in.
Catsam said security can always be ratcheted up, but then comes the issue of how much convenience people are willing to give up for the sake of safety.
"They could start saying you can bring whatever kind of backpack you want but you have to go through an X-ray system like you do at the airport," he said. "It would take forever and we'd adjust, but I'm not sure what we'll discover or if we'll be making anything really safer."
Marciani, on the other hand, envisions a day when backpacks are as obsolete at a stadium as the bulky transistor radios that fans once brought along so they could listen to play-by-play as they watched the game.
"I think it's just one less aggravation we'd have to put up with," he said. "I'd just say, 'Why backpacks at a stadium?' I don't think we need them."
___
AP Sports Writers Pat Graham in Denver, Howard Fendrich in Washington, Stephen Wilson, Rob Harris, Steve Douglas and Chris Lehourites in London, Tales Azzoni in Sao Paolo, Brazil, Janie McCauley in San Francisco, Jon Krawczynski in Minneapolis, Graham Dunbar in Geneva, Jimmy Golen in Boston, Ben Walker and Ron Blum in New York, David Ginsburg in Baltimore and Bernie Wilson in San Diego and Associated Press reporter Peter Banda contributed to this report.
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Friday, April 26, 2013
Congress approves bill to end delays in flights
A United Airlines jet departs in view of the air traffic control tower at Seattle-Tacoma International Airport Tuesday, April 23, 2013, in Seattle. A day after flight delays plagued much of the U.S., air travel is smoother Tuesday. But the government is warning passengers that the situation can change by the hour as it runs the nation's air traffic control system with a smaller staff. Airlines and members of Congress urged the Federal Aviation Administration to find other ways to make mandatory budget cuts besides furloughing controllers. While delays haven't been terrible yet, the airlines are worried about the long-term impact late flights will have on their budgets and on fliers. (AP Photo/Elaine Thompson)
A United Airlines jet departs in view of the air traffic control tower at Seattle-Tacoma International Airport Tuesday, April 23, 2013, in Seattle. A day after flight delays plagued much of the U.S., air travel is smoother Tuesday. But the government is warning passengers that the situation can change by the hour as it runs the nation's air traffic control system with a smaller staff. Airlines and members of Congress urged the Federal Aviation Administration to find other ways to make mandatory budget cuts besides furloughing controllers. While delays haven't been terrible yet, the airlines are worried about the long-term impact late flights will have on their budgets and on fliers. (AP Photo/Elaine Thompson)
WASHINGTON (AP) ? Congress hurried to approve legislation Friday that will end the furloughs of air traffic controllers that have delayed hundreds of flights daily, infuriating travelers and causing political headaches for lawmakers.
The House approved the measure on a 361-41 vote, a day after the Senate agreed to the bill. Friday's vote came as lawmakers prepared to leave town for a weeklong spring recess, a break that would have been less pleasant if they were confronted by constituents upset over travel delays.
Republicans accused the Obama administration of purposely furloughing controllers to pressure Congress to replace $85 billion in across-the-board spending cuts ? known as the sequester ? that took effect last month at government agencies.
"The administration has played shameful politics with the sequester at the cost of hard-working American families," said Rep. Tom Latham, R-Iowa.
The White House and Democrats have argued that by law, the administration has little room to decide where the cuts fall. They want Congress to work on legislation lifting all of the cuts, which lawmakers noted have also caused reductions in Head Start preschool programs, benefits for the long-term unemployed and medical research.
White House press secretary Jay Carney said the president would sign the new bill, but he added, "The problem is this is just a Band-Aid solution."
During House debate, House Minority Leader Nancy Pelosi, D-Calif., had a similar complaint.
"How can we sit there and say, 'Four million Meals on Wheels for seniors, gone, but that's not important. Over 70,000 children off Head Start, but that's not important," Pelosi said.
The Federal Aviation Administration has furloughed the controllers as part of the government-wide reductions. The bill would let the FAA use up to $253 million from airport improvement and other accounts to end the furloughs through the Sept. 30 end of the federal fiscal year.
In addition to restoring full staffing by controllers, the available funds can be used for other FAA operations, including preventing the closure of small airport towers around the country. The FAA had said it would shut the facilities to meet its share of the spending cuts.
The FAA said there had been at least 863 flights delayed on Wednesday "attributable to staffing reductions resulting from the furlough."
Administration officials participated in the negotiations that led to the deal and evidently registered no objections.
Sen. Susan Collins, R-Maine, a key participant in the talks, said the legislation would "prevent what otherwise would have been intolerable delays in the air travel system, inconveniencing travelers and hurting the economy."
Senate approval Thursday night followed several hours of pressure-filled, closed-door negotiations, and came after most senators had departed the Capitol on the assumption that the talks had fallen short.
For the White House and Senate Democrats, the discussions on legislation relating to one relatively small slice of the $85 billion in spending cuts marked a shift in position in a long-running struggle with Republicans over budget issues. Similarly, the turn of events marked at least modest vindication of a decision by the House GOP last winter to finesse some budget struggles in order to focus public attention on the across-the-board cuts in hopes they would gain leverage over President Barack Obama.
The Professional Aviation Safety Specialists, a union that represents FAA employees, reported a number of incidents it said were due to the furloughs.
In one case, it said several flights headed for Long Island MacArthur Airport in New York were diverted on Wednesday when a piece of equipment failed. "While the policy for this equipment is immediate restoral, due to sequestration and furloughs it was changed to next-day restoral," the union said.
The airlines, too, had pressed Congress to restore the FAA to full staffing.
In an interview Wednesday, Robert Isom, chief operations officer of US Airways, said, "In the airline business, you try to eliminate uncertainty. Some factors you can't control, like weather. It (the FAA issue) is worse than the weather."
In a shift, first the White House and then senior Democratic lawmakers signaled a willingness in the past two days to support legislation that alleviates the budget crunch at the FAA, while leaving the balance of the $85 billion to remain in effect.
Obama favors a comprehensive agreement that replaces the entire $85 billion in across-the-board cuts as part of a broader deficit-reduction deal that includes higher taxes and spending cuts.
Officials estimate it would cost slightly more than $200 million to restore air traffic controllers to full staffing, and an additional $50 million to keep open smaller air traffic towers around the country that the FAA has proposed closing.
___
Associated Press writers Joan Lowy, Henry C. Jackson and Alan Fram in Washington and David Koenig in Dallas contributed to this report.
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After brain injury, new astrocytes play unexpected role in healing
Apr. 24, 2013 ? The production of a certain kind of brain cell that had been considered an impediment to healing may actually be needed to staunch bleeding and promote repair after a stroke or head trauma, researchers at Duke Medicine report.
These cells, known as astrocytes, can be produced from stem cells in the brain after injury. They migrate to the site of damage where they are much more effective in promoting recovery than previously thought. This insight from studies in mice, reported online April 24, 2013, in the journal Nature, may help researchers develop treatments that foster brain repair.
"The injury recovery process is complex," said senior author Chay T. Kuo, M.D., PhD, George W. Brumley Assistant Professor of Cell Biology, Pediatrics and Neurobiology at Duke University. "There is a lot of interest in how new neurons can stimulate functional recovery, but if you make neurons without stopping the bleeding, the neurons don't even get a chance. The brain somehow knows this, so we believe that's why it produces these unique astrocytes in response to injury."
Each year, more than 1.7 million people in the United States suffer a traumatic brain injury, according to the Centers for Disease Control and Prevention. Another 795,000 people a year suffer a stroke. Few therapies are available to treat the damage that often results from such injuries.
Kuo and colleagues at Duke are interested in replacing lost neurons after a brain injury as a way to restore function. Once damaged, mature neurons cannot multiply, so most research efforts have focused on inducing brain stem cells to produce more immature neurons to replace them.
This strategy has proved difficult, because in addition to making neurons, neural stem cells also produce astrocytes and oligodendrocytes, known as glial cells. Although glial cells are important for maintaining the normal function of neurons in the brain, the increased production of astrocytes from neural stem cell has been considered an unwanted byproduct, causing more harm than good. Proliferating astrocytes secrete proteins that can induce tissue inflammation and undergo gene mutations that can lead to aggressive brain tumors.
In their study of mice, the Duke team found an unexpected insight about the astrocytes produced from stem cells after injury. Stem cells live in a special area or "niche" in the postnatal/adult brain called the subventricular zone, and churn out neurons and glia in the right proportions based on cues from the surrounding tissue.
After an injury, however, the subventricular niche pumps out more astrocytes. Significantly, the Duke team found they are different from astrocytes produced in most other regions of the brain. These cells make their way to the injured area to help make an organized scar, which stops the bleeding and allows tissue recovery.
When the generation of these astrocytes in the subventricular niche was experimentally blocked after a brain injury, hemorrhaging occurred around the injured areas and the region did not heal. Kuo said the finding was made possible by insights about astrocytes from Cagla Eroglu, PhD, whose laboratory next door to Kuo's conducts research on astrocyte interactions with neurons.
"Cagla and I started at Duke together and have known each other since our postdoctoral days," Kuo said. "To have these stem cell-made astrocytes express a unique protein that Cagla understands more than anyone else, it's just a wonderful example of scientific serendipity and collaboration."
Additionally, Kuo said first author Eric J. Benner, M.D., PhD, a former postdoctoral fellow who now has his own laboratory at Duke, provided key clinical correlations on brain injury as a physician-scientist and practicing neonatologist in the Jean and George Brumley Jr. Neonatal-Perinatal Research Institute.
"We are very excited about this innate flexibility in neural stem cell behavior to know just what to do to help the brain after injury," Kuo said. "Since bleeding in the brain after injury is a common and serious problem for patients, further research into this area may lead to effective therapies for accelerated brain recovery after injury."
In addition to Kuo, Eroglu and Benner, authors include Dominic Luciano, Rebecca Jo, Khadar Abdi, Patricia Paez-Gonzalez, Huaxin Sheng, David Warner and Chunlei Liu.
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The above story is reprinted from materials provided by Duke University Medical Center.
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Journal Reference:
- Eric J. Benner, Dominic Luciano, Rebecca Jo, Khadar Abdi, Patricia Paez-Gonzalez, Huaxin Sheng, David S. Warner, Chunlei Liu, Cagla Eroglu, Chay T. Kuo. Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4. Nature, 2013; DOI: 10.1038/nature12069
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/zIrBOIqCR0I/130424132707.htm
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3M cuts 2013 outlook on falling electronics demand
By Ernest Scheyder
(Reuters) - Diversified U.S. manufacturer 3M Co cut its 2013 profit forecast on Thursday, citing weakening demand for electronics products as well as foreign currency fluctuations.
The lowered outlook came after first-quarter profit and revenue both missed Wall Street expectations.
3M, which makes a range of products from Post-It notes to films used in television screens, blamed falling sales in its consumer electronics segment.
Executives had expected weak demand for electronic insulation, computer touch screen materials as well as fluids used to make computer chips, but they said actual sales were worse than feared.
"We expected a challenging start to the year, but in fact market conditions were tougher than we had expected," Chief Executive Inge Thulin said on a conference call with investors.
While a 56 percent drop in pension payments boosted first-quarter margins, analysts were wary as margin strength wasn't more reliant on higher sales.
Additionally, the company changed its reporting segments on January 1, making it difficult for analysts to compare performance to prior years and track results, William Blair & Co analyst Nick Heymann said.
"This is a little more complex than normal," Heymann said.
3M now expects to earn $6.60 to $6.85 per share this year, a range mostly below the $6.82 average analyst estimate, according to Thomson Reuters I/B/E/S.
3M previously had expected to earn $6.70 to $6.95 per share this year.
Also, the rising value of the U.S. dollar compared to other global currencies harmed results, executives said. Before, the company had not expected foreign currency changes to harm 2013 results, but now it was seen cutting revenue by 1.5 percent.
Its stock dropped 3.5 percent to $104.09 in mid-morning trading. It has gained about 16 percent this year, outpacing the Dow Jones industrial average's roughly 12 percent rise.
REVENUE RISES
St. Paul, Minnesota-based 3M posted first-quarter profit of $1.13 billion, or $1.61 per share, compared with $1.13 billion, or $1.59 per share, in the year-earlier period.
Profit per share missed analysts' estimates of $1.65. The number of outstanding shares fell, boosting the most recent earnings per share.
Revenue rose 2 percent to $7.63 billion, missing the $7.81 billion estimate from analysts.
Thulin, who took the top job last year, began a restructuring in January. He merged 3M's security and traffic-safety units, eliminating about 300 jobs, and identified other units that 3M would need to fix, sell or close.
Thulin has said 3M needs to prune its broad portfolio of products, and likely to focus on fewer but larger takeovers.
(Reporting by Ernest Scheyder; Editing by Gerald E. McCormick, Maureen Bavdek and Jeffrey Benkoe)
Source: http://news.yahoo.com/3m-quarterly-profit-slightly-2013-outlook-cut-115703087--sector.html
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Thursday, April 25, 2013
A Look Inside Afghanistan's Almost-Apple Store
Source: http://feeds.gawker.com/~r/gizmodo/full/~3/lD-74FUd0XE/a-look-inside-afghanistans-almost+apple-store
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Twitter co-founder says more techy leaders needed
NEW YORK (AP) ? Twitter co-founder Jack Dorsey thinks there needs to be more leaders who understand how to use technology.
Speaking at a New York City campaign event for a local political hopeful Wednesday, Dorsey said more leaders are needed who get technology and know how to use it.
He says technology can change governments, not just disrupt them.
The billionaire entrepreneur behind the popular social media service has hinted he may one day want to be mayor of New York. In an interview aired on CBS' "60 Minutes" last month, correspondent Lara Logan said Dorsey is serious about moving to the Big Apple someday and running for mayor.
Dorsey did not take any questions after addressing the crowd that gathered in support of public advocate candidate Reshma Saujani (RUHSH'-muh sow-JAHN'-ee).
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Wednesday, April 24, 2013
Senate duo dials back anti-big bank proposal
By Douwe Miedema
WASHINGTON (Reuters) - Legislation to force U.S. banks to drastically raise their capital buffers - a proposal that has been criticized as a veiled attempt to break up the biggest banks - was presented in a slightly weakened form by two senators on Wednesday.
The two, Sherrod Brown, an Ohio Democrat, and David Vitter, a Louisiana Republican, want to ditch a global accord on capital standards known as Basel III and put more straightforward caps on how much banks can borrow.
The bill, which adds to a rising chorus of big-bank critics in Washington even if it stands little chance of getting adopted, requires banks with more than $500 billion in assets to have at least 15 percent of shareholder equity.
In a draft proposal, Brown and Vitter had set a minimum capital ratio of 10 percent for all banks, but the final text of the bill lowered that to 8 percent for those banks with more than $50 billion in assets.
Bank regulators could set the capital ratio for banks that were even smaller, the bill said.
"This is a bank break-up proposal," said Tony Fratto, who works at consulting firm Hamilton Place Strategies. "Mandating new and punitive capital charges, and walking away from international agreements ... is misguided."
The debate about whether Washington has done enough to stave off the risk of a taxpayer bailout of Wall Street has heated up in recent weeks, with politicians and even some regulators calling to do more to prevent the next crisis.
Basel III calls on banks to hold up to 13 percent of capital, but that level is determined based on the riskiness of assets, making it far less demanding than the Brown-Vitter proposal.
Many lawmakers, banks and regulators have also criticized the Basel approach as too complicated.
There is little chance of political consensus on any plan to carve up banks such as JPMorgan Chase, Citigroup or Bank of America, though another major mishap at one of these banks might change that.
The Senate last month approved a largely symbolic measure to eliminate a "subsidy" banks receive in the form of cheaper borrowing, because markets assume that governments will always bail them out if they land in trouble.
Small banks grouped together in the Independent Community Bankers of America (ICBA) welcomed the law, which also provides relief for small banks from a range of other rules that have been written after the financial crisis.
Representative Jeb Hensarling - a Texas Republican who chairs the influential House Financial Services Committee - equally promised small banks relief from the increasing regulatory burden at an ICBA conference on Wednesday.
Democrats and Republicans in the committee were negotiating about a "bipartisan regulatory relief bill", Hensarling said. He declined to say what would be in the bill.
(Reporting by Douwe Miedema; Editing by Steve Ortlofsky)
Source: http://news.yahoo.com/senate-duo-dials-back-anti-big-bank-proposal-225710549--sector.html
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Nicole Kidman and Ang Lee join starry Cannes jury
PARIS (AP) ? The Cannes Film Festival says Oscar winners Nicole Kidman, Christopher Waltz and Ang Lee will join this year's competition jury.
Steven Spielberg will lead 2013's jury that will also include Romanian director Cristian Mungiu, who won the festival's prize for best screenplay in 2012 for "Beyond The Hills," French actor Daniel Auteuil, Indian actress Vidya Balan, Scottish director Lynne Ramsay and Japanese director Naomi Kawase, according to a statement published Wednesday.
They'll decide which of the 19 films in competition will win the coveted Palme d'Or award on May 26, the French Riviera festival's top accolade.
Source: http://news.yahoo.com/nicole-kidman-ang-lee-join-starry-cannes-jury-131817094.html
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Tuesday, April 23, 2013
Marquer l'ensemble du forum comme lu . - GROSSE HOTLINE - La ...
Bonjour,
?
?a fait plusieur fois que j'essaye de marquer le forum commr "lu"dans son ensemble mais quand je clique sur le bouton pr?vu ? cet effet en bas de la page, il m'ouvre un mini menu avec comme choix "report center " et "membre" .
Bon alors, ?a n'emp?che pas d'aller marquer comme lu chaque gros forum, mais ?a serait tout de m?me plus pratique de pouvoir le faire en un seul coup. Est-ce qu'il y a un autre moyen de faire cette op?ration ?
?
Merci !
Source: http://www.lagrosseradio.com/forums/index.php?showtopic=44680
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Chesapeake, Bank of New York, square off in bond trial
By Bernard Vaughan
NEW YORK (Reuters) - Chesapeake Energy Corp began an expedited trial on Tuesday against Bank of New York Mellon Corp over the energy company's effort to redeem $1.3 billion of notes at par.
The proceeding in Manhattan federal court comes less than two months after Chesapeake sued the bank, the trustee for the bonds, seeking to prevent it from interfering with the redemption.
The dispute is separate from other legal issues involving Chesapeake, the second-largest natural gas producer in the United States.
Chesapeake, which faces a projected $3 billion cash shortfall this year, argues that it had until this past March 15 to notify noteholders that it intended to redeem the notes, which have an interest rate of 6.775 percent and mature in 2019, at par.
If it is not able to, the company will pay about $100 million in interest, one of its attorneys, Stephen Ascher, said in court on Tuesday.
The bank disagrees, arguing that Chesapeake had to complete any par redemption by March 15, and that any redemption thereafter requires it to pay an additional $400 million make-whole payment to investors.
The trial is expected to run through early next week. U.S. District Judge Paul Engelmayer is hearing the case without a jury.
At the trial's start, Ascher said the company's witnesses will include Chesapeake Chief Financial Officer Domenic Dell'Osso, who helped draft the bond offering. They will testify that it was understood that Chesapeake would have until March 15 to notify investors that it intended to redeem the bonds early, he said.
The bank's case would be based on the argument that Chesapeake's witnesses do not matter, Ascher told the judge. He said Bank of New York Mellon did not participate in drafting terms of the bond offering and is the only party involved that disputes Chesapeake's view of the March 15 deadline.
"Chesapeake's interpretation of the text is the only reasonable interpretation," Ascher said.
But Steven Bierman, a lawyer for Bank of New York Mellon, said that Chesapeake's evidence is irrelevant. There was no understanding between Chesapeake and Bank of New York Mellon that the energy company had only to issue a redemption notice by March 15, he said.
Further, there is no written communication that discussed the early redemption period as only requiring notice, Bierman argued.
Aubrey McClendon, Chesapeake's former chief executive officer who had been appointed by the company's board to oversee pricing of the debt offering, said in a deposition that he "didn't know anything" about the portion of the contract in question, Bierman said.
"March 15 is a bright line between redemption at par and redemption at the make-whole payment," Bierman said.
Chesapeake is facing several other legal issues, including a probe by the U.S. Securities and Exchange Commission into a perk that granted McClendon a stake in company wells and a U.S. Department of Justice investigation into possible antitrust violations in Michigan land deals.
McClendon left the company on April 1.
The case is Chesapeake Energy Corp v. Bank of New York Mellon Trust Co, U.S. District Court, Southern District of New York, No. 13-01582.
(Reporting By Bernard Vaughan; Editing by Martha Graybow and Andrea Ricci)
Source: http://news.yahoo.com/chesapeake-bank-york-square-off-bond-trial-174929998--sector.html
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Using black holes to measure the universe's rate of expansion
Apr. 22, 2013 ? Radiation emitted in the vicinity of black holes could be used to measure distances of billions of light years, says TAU researcher
A few years ago, researchers revealed that the universe is expanding at a much faster rate than originally believed -- a discovery that earned a Nobel Prize in 2011. But measuring the rate of this acceleration over large distances is still challenging and problematic, says Prof. Hagai Netzer of Tel Aviv University's School of Physics and Astronomy.
Now, Prof. Netzer, along with Jian-Min Wang, Pu Du and Chen Hu of the Institute of High Energy Physics of the Chinese Academy of Sciences and Dr. David Valls-Gabaud of the Observatoire de Paris, has developed a method with the potential to measure distances of billions of light years with a high degree of accuracy. The method uses certain types of active black holes that lie at the center of many galaxies. The ability to measure very long distances translates into seeing further into the past of the universe -- and being able to estimate its rate of expansion at a very young age.
Published in the journal Physical Review Letters, this system of measurement takes into account the radiation emitted from the material that surrounds black holes before it is absorbed. As material is drawn into a black hole, it heats up and emits a huge amount of radiation, up to a thousand times the energy produced by a large galaxy containing 100 billion stars. For this reason, it can be seen from very far distances, explains Prof. Netzer.
Solving for unknown distances
Using radiation to measure distances is a general method in astronomy, but until now black holes have never been used to help measure these distances. By adding together measurements of the amount of energy being emitted from the vicinity of the black hole to the amount of radiation which reaches Earth, it's possible to infer the distance to the black hole itself and the time in the history of the universe when the energy was emitted.
Getting an accurate estimate of the radiation being emitted depends on the properties of the black hole. For the specific type of black holes targeted in this work, the amount of radiation emitted as the object draws matter into itself is actually proportional to its mass, say the researchers. Therefore, long-established methods to measure this mass can be used to estimate the amount of radiation involved.
The viability of this theory was proved by using the known properties of black holes in our own astronomical vicinity, "only" several hundred million light years away. Prof. Netzer believes that his system will add to the astronomer's tool kit for measuring distances much farther away, complimenting the existing method which uses the exploding stars called supernovae.
Illuminating "Dark Energy"
According to Prof. Netzer, the ability to measure far-off distances has the potential to unravel some of the greatest mysteries of the universe, which is approximately 14 billion years old. "When we are looking into a distance of billions of light years, we are looking that far into the past," he explains. "The light that I see today was first produced when the universe was much younger."
One such mystery is the nature of what astronomers call "dark energy," the most significant source of energy in the present day universe. This energy, which is manifested as some kind of "anti-gravity," is believed to contribute towards the accelerated expansion of the universe by pushing outwards. The ultimate goal is to understand dark energy on physical grounds, answering questions such as whether this energy has been consistent throughout time and if it is likely to change in the future.
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The above story is reprinted from materials provided by American Friends of Tel Aviv University.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Jian-Min Wang, Pu Du, David Valls-Gabaud, Chen Hu, Hagai Netzer. Super-Eddington Accreting Massive Black Holes as Long-Lived Cosmological Standards. Physical Review Letters, 2013; 110 (8) DOI: 10.1103/PhysRevLett.110.081301
Note: If no author is given, the source is cited instead.
Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/6XRfCgxonw8/130422123040.htm
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LG's NYC press event aims to 'share the genius' of the Optimus G Pro
LG's just shed some much-needed light on its May 1st New York event. Turns out the "genius" the company will be celebrating stands for Atlas Genius -- as in the band -- and the star of this fete: the Optimus G Pro. We've already seen and very favorably reviewed the global model of LG's performance flagship (for the G's successor, you'll have to wait until Q3) and now it looks like the US is in store for a potential carrier-branded version of its own. If it arrives internally unmolested, we're looking at a 5.5-inch 1080p True HD IPS+ display, Snapdragon 600 and a 2.1-megapixel / 13-megapixel camera setup capable of dual video recording. We'll be on-site for this stateside debut, so stay tuned for the full monty.
Filed under: Cellphones, Wireless, Mobile, LG
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Monday, April 22, 2013
Screening detects ovarian cancer using neighboring cells
[ | E-mail | Share ]
Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University
Study results could translate into a minimally invasive early detection method
Pioneering biophotonics technology developed at Northwestern University is the first screening method to detect the early presence of ovarian cancer in humans by examining cells easily brushed from the neighboring cervix or uterus, not the ovaries themselves.
A research team from Northwestern and NorthShore University HealthSystem (NorthShore) conducted an ovarian cancer clinical study at NorthShore. Using partial wave spectroscopic (PWS) microscopy, they saw diagnostic changes in cells taken from the cervix or uterus of patients with ovarian cancer even though the cells looked normal under a microscope.
The results have the potential to translate into a minimally invasive early detection method using cells collected by a swab, exactly like a Pap smear. No reliable early detection method for ovarian cancer currently exists.
In previous Northwestern-NorthShore studies, the PWS technique has shown promising results in the early detection of colon, pancreatic and lung cancers using cells from neighboring organs. If commercialized, PWS could be in clinical use for one or more cancers in approximately five years.
The ovarian cancer study was published this month by the International Journal of Cancer.
PWS uses light scattering to examine the architecture of cells at the nanoscale and can detect profound changes that are the earliest known signs of carcinogenesis. These changes can be seen in cells far from the tumor site or even before a tumor forms.
"We were surprised to discover we could see diagnostic changes in cells taken from the endocervix in patients who had ovarian cancer," said Vadim Backman, who developed PWS at Northwestern. "The advantage of nanocytology -- and why we are so excited about it -- is we don't need to wait for a tumor to develop to detect cancer."
Backman is a professor of biomedical engineering at the McCormick School of Engineering and Applied Science. He and his longtime collaborator, Hemant K. Roy, M.D., formerly of NorthShore, have been working together for more than a decade and conducting clinical trials of PWS at NorthShore for four years. Backman and Roy both are authors of the paper.
"The changes we have seen in cells have been identical, no matter which organ we are studying," Backman said. "We have stumbled upon a universal cell physiology that can help us detect difficult cancers early. If the changes are so universal, they must be very important."
Ovarian cancer, which ranks fifth in cancer fatalities among American women, usually goes undetected until it has spread elsewhere. The cancer is difficult to treat at this late stage and often is fatal.
"This intriguing finding may represent a breakthrough that would allow personalization of screening strategies for ovarian cancer via a minimally intrusive test that could be coupled to the Pap smear," Roy said.
At the time of the ovarian cancer study, Roy was director of gastroenterology research at NorthShore and worked with Jean A. Hurteau, M.D., a gynecological oncologist at NorthShore. (Hurteau is an author of the paper.) Roy is now chief of the section of gastroenterology at Boston University School of Medicine and Boston Medical Center.
The study included a total of 26 individuals. For cells taken from the endometrium (part of the uterus), there were 26 patients (11 with ovarian cancer and 15 controls); for cells taken from the endocervix, there were 23 patients (10 with ovarian cancer and 13 controls). The small size of the study reflects the difficulty in recruiting ovarian cancer patients.
Cells were placed on slides and then examined using PWS. The results showed a significant increase in the disorder of the nanoarchitecture of epithelial cells obtained from cancer patients compared to controls for both the endometrium and endocervix studies.
The cells for the ovarian cancer study were taken from the cervix and uterus. For the earlier lung cancer study, cells were brushed from the cheek. For the colon, cells came from the rectum, and for the pancreas, cells came from the duodenum. Cells from these neighboring organs showed changes at the nanoscale when cancer was present.
PWS can detect cell features as small as 20 nanometers, uncovering differences in cells that appear normal using standard microscopy techniques. PWS measures the disorder strength of the nanoscale organization of the cell, which is a strong marker for the presence of cancer in the organ or in a nearby organ.
The PWS-based test makes use of the "field effect," a biological phenomenon in which cells located some distance from the malignant or pre-malignant tumor undergo molecular and other changes.
###
The paper is titled "Insights into the field carcinogenesis of ovarian cancer based on the nanocytology of endocervical and endometrial epithelial cells." The paper is available at http://onlinelibrary.wiley.com/doi/10.1002/ijc.28122/abstract.
In addition to Backman, Roy and Hurteau, other authors of the paper include Dhwanil Damania, Hariharan Subramanian, Lusik Cherkezyan, all from Northwestern, and Dhananjay Kunte, Nela Krosnjar and Maitri Shah, all from NorthShore University HealthSystem.
Editor's note: Backman, Roy and Subramanian are co-founders and/or shareholders in Nanocytomics LLC.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
[ | E-mail | Share ]
Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University
Study results could translate into a minimally invasive early detection method
Pioneering biophotonics technology developed at Northwestern University is the first screening method to detect the early presence of ovarian cancer in humans by examining cells easily brushed from the neighboring cervix or uterus, not the ovaries themselves.
A research team from Northwestern and NorthShore University HealthSystem (NorthShore) conducted an ovarian cancer clinical study at NorthShore. Using partial wave spectroscopic (PWS) microscopy, they saw diagnostic changes in cells taken from the cervix or uterus of patients with ovarian cancer even though the cells looked normal under a microscope.
The results have the potential to translate into a minimally invasive early detection method using cells collected by a swab, exactly like a Pap smear. No reliable early detection method for ovarian cancer currently exists.
In previous Northwestern-NorthShore studies, the PWS technique has shown promising results in the early detection of colon, pancreatic and lung cancers using cells from neighboring organs. If commercialized, PWS could be in clinical use for one or more cancers in approximately five years.
The ovarian cancer study was published this month by the International Journal of Cancer.
PWS uses light scattering to examine the architecture of cells at the nanoscale and can detect profound changes that are the earliest known signs of carcinogenesis. These changes can be seen in cells far from the tumor site or even before a tumor forms.
"We were surprised to discover we could see diagnostic changes in cells taken from the endocervix in patients who had ovarian cancer," said Vadim Backman, who developed PWS at Northwestern. "The advantage of nanocytology -- and why we are so excited about it -- is we don't need to wait for a tumor to develop to detect cancer."
Backman is a professor of biomedical engineering at the McCormick School of Engineering and Applied Science. He and his longtime collaborator, Hemant K. Roy, M.D., formerly of NorthShore, have been working together for more than a decade and conducting clinical trials of PWS at NorthShore for four years. Backman and Roy both are authors of the paper.
"The changes we have seen in cells have been identical, no matter which organ we are studying," Backman said. "We have stumbled upon a universal cell physiology that can help us detect difficult cancers early. If the changes are so universal, they must be very important."
Ovarian cancer, which ranks fifth in cancer fatalities among American women, usually goes undetected until it has spread elsewhere. The cancer is difficult to treat at this late stage and often is fatal.
"This intriguing finding may represent a breakthrough that would allow personalization of screening strategies for ovarian cancer via a minimally intrusive test that could be coupled to the Pap smear," Roy said.
At the time of the ovarian cancer study, Roy was director of gastroenterology research at NorthShore and worked with Jean A. Hurteau, M.D., a gynecological oncologist at NorthShore. (Hurteau is an author of the paper.) Roy is now chief of the section of gastroenterology at Boston University School of Medicine and Boston Medical Center.
The study included a total of 26 individuals. For cells taken from the endometrium (part of the uterus), there were 26 patients (11 with ovarian cancer and 15 controls); for cells taken from the endocervix, there were 23 patients (10 with ovarian cancer and 13 controls). The small size of the study reflects the difficulty in recruiting ovarian cancer patients.
Cells were placed on slides and then examined using PWS. The results showed a significant increase in the disorder of the nanoarchitecture of epithelial cells obtained from cancer patients compared to controls for both the endometrium and endocervix studies.
The cells for the ovarian cancer study were taken from the cervix and uterus. For the earlier lung cancer study, cells were brushed from the cheek. For the colon, cells came from the rectum, and for the pancreas, cells came from the duodenum. Cells from these neighboring organs showed changes at the nanoscale when cancer was present.
PWS can detect cell features as small as 20 nanometers, uncovering differences in cells that appear normal using standard microscopy techniques. PWS measures the disorder strength of the nanoscale organization of the cell, which is a strong marker for the presence of cancer in the organ or in a nearby organ.
The PWS-based test makes use of the "field effect," a biological phenomenon in which cells located some distance from the malignant or pre-malignant tumor undergo molecular and other changes.
###
The paper is titled "Insights into the field carcinogenesis of ovarian cancer based on the nanocytology of endocervical and endometrial epithelial cells." The paper is available at http://onlinelibrary.wiley.com/doi/10.1002/ijc.28122/abstract.
In addition to Backman, Roy and Hurteau, other authors of the paper include Dhwanil Damania, Hariharan Subramanian, Lusik Cherkezyan, all from Northwestern, and Dhananjay Kunte, Nela Krosnjar and Maitri Shah, all from NorthShore University HealthSystem.
Editor's note: Backman, Roy and Subramanian are co-founders and/or shareholders in Nanocytomics LLC.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-04/nu-sdo042213.php
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